A loxP-flanked neo cassette was inserted at 5' of exon 6 and a third loxP sequence downstream of exon 6. Cre mediated recombination removed the neo cassette, creating an allele with exon 6 flanked by loxP sites. (J:206816)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count