Exons 3-5 were flanked by loxP sites. A neo with a third loxP site was located downstream of the floxed exons. Cre-mediated recombination removed the selection cassette. (J:208380)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count