The transgene expresses a full-length mouse Ubqln1 cDNA under the control of the CMV enhancer/chicken beta-actin promoter. Immunoblot analysis indicates striking overexpression in the brain, heart, liver and skeletal muscle with lower levels of overexpression seen in other tissues. (J:206930)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count