This allele, from project Wee2-5717J-4922, was generated by injecting Cas9 RNA and guide sequence GACTGCACAAGACATCGG into fertilized C57BL/6NJ oocytes, which resulted in an 8 bp deletion CAAGACAT in exon2 beginning at Chromosome 6 positive strand position 40444071 bp (GRCm38). It is predicted to cause a frameshift mutation with an amino acid change of glutamine to arginine after residue 31 and early truncation 13 residues later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count