This allele, from project Wee2-5717J-4922, was generated by injecting Cas9 RNA and guide sequence GACTGCACAAGACATCGG into fertilized C57BL/6NJ oocytes, which resulted in an 8 bp deletion CAAGACAT in exon2 beginning at Chromosome 6 positive strand position 40444071 bp (GRCm38). It is predicted to cause a frameshift mutation with an amino acid change of glutamine to arginine after residue 31 and early truncation 13 residues later. (J:188991)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NJ
Endonuclease-mediated
Intragenic deletion
Not Specified
1
2
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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