A loxP site was inserted into the promoter. An FRT-flanked neomycin resistance cassette with a loxP site was inserted into intron 2. Flp-mediated recombination removed the selection cassette and left exon 1 floxed. (J:211440)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count