This transgene contains the promoter of the CD68 antigen gene driving expression of human B cell leukemia/lymphoma 2 (BCL2). Immunoblot analysis demonstrates expression of human BCL2 in dendritic cells (DCs) and bone-marrow derived macrophages (BMMs) of mice of this transgenic line, but not in BMMs or DCs of non-transgenic littermates. (J:211458)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129 x C57BL/6
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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