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The Merkel cell polyomavirus (MCPyV) early region, isolated from MCC tumor specimen MCCw168 (MCPyV168; GenBank: KC426954.1), was PCR amplified and cloned into the pBigT vector between XhoI and NotI restriction sites. A 6kb fragment containing the neomycin resistance gene and triple SV40 polyadenylation transcription terminators flanked by two loxP sites (loxP-stop-loxP, or LSL), MCPyV168, and bovine growth hormone polyadenylation terminator were cut from the pBigT vector and cloned into the pROSA26PA vector between PacI and AscI restriction sites. (J:219802)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
