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This transgene consists of the Myh6 promoter driving expression of a full-length human TNNT2 cDNA containing a T to C substitution at position 520 that results in the R141W mutation. Northern blot and immunohistochemistry confirmed expression. Three lines were established: 1, 13, and 16, however the pound symbol (#) is used because the lines are pooled. (J:211769)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
