Part of exon 1 was replaced with a loxP site, nuclear localized lacZ reporter, loxP site, nuclear localized GFP (H2B-GFP) reporter and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. Western blot analysis confirmed the absence of protein expression in bone marrow cells. (J:208085)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count