Two loxP sites flanking exon 5-10 and an Frt-flanked neomycin selection cassette were inserted in the upstream intron. Flp-mediated recombination removed the neomycin cassette and left exons 5-10 floxed. (J:208092)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count