Exon 3 of the mouse Phox2b gene was flanked by loxP sites. An FRT-flanked neomycin cassette, human exon 3 (modified with an 8 bp deletion, GGCCCGGG) and associated with an EGFP reporter, was inserted downstream. Flp-mediated recombination removed the selection cassette. (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
Insertion
--
1
5
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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