Exon 3 of the mouse Phox2b gene was flanked by loxP sites. An FRT-flanked neomycin cassette, human exon 3 (modified with an 8 bp deletion, GGCCCGGG) and associated with an EGFP reporter, was inserted downstream. Flp-mediated recombination removed the selection cassette. (J:101977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count