An FRT flanked lacZ/neo construct along with a loxP site was inserted upstream of exon 5 and a second loxP site was left in place 3' of exon 5. The 5' selection cassette was then removed by flp recombinase expression leaving exon 5 flanked by loxP sites. Subsequent cre expression excised exon 5. (J:206155)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
Intragenic deletion
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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