The entire open reading frame of Tectb followed by an IRES, the EGFP open reading frame and a poly(A) addition signal from SV40 were fused out of frame with the start codon. The mRNA transcribed from the targeted allele fails to express Tectb but does express EGFP, acting as a reporter in those cells expressing the endogenous gene. (J:211102)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv
Targeted
Insertion
--
1
7
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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