Wild-type mouse alpha-synuclein cDNA expression is driven by the Thy1 regulatory sequences. Three lines were created: 1S13, 1S14, and 1S16. This line expresses mRNA and protein levels in the brain that are up to 6-fold above endogenous levels. (J:177661)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count