A floxed neomycin resistance cassette was inserted within intron 1 and a single loxP site 5' to exon 1 by homologous recombination. Cre-mediated recombination removed the selection cassette and left exon 1 floxed. (J:158947)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count