Exons 2 through 6 were replaced with a loxP site, the cDNA fused to EGFP, an FRT-flanked neomycin resistance cassette, a loxP site and STOP/polyadenylation cassette. Cre-mediated recombination removed the fusion cDNA and selection cassette. (J:210870)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count