This transgene comprises a genomic DNA fragment containing the coding region of the chicken lysozyme (also called hen egg lysozyme, HEL) gene joined to the 5' promoter elements of the liver-specific mouse abumin gene. The mean HEL concentration, measured by enzyme-linked immunosorbent assay (ELISA), in sera of mice of this line is 58 ng/ml; serum HEL levels in female mice are approximately twice those in males. (J:104190, J:127344, J:210801)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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