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The bi-directional tetracycline-responsive operator drives inducible expression of the human MYCN cDNA and firefly luciferase. In double transgenic mice also expressing the tetracycline transactivating or reverse transactivating element (tTA or rtTA), expression of MYCN can be regulated by doxycycline administration or removal. (J:160518)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
