This transgene contained the bovine thyroglobulin (TG) promoter and a translocation fusion product of human TPR and human NTRK1, something observed in human papillary thyroid carcinomas. Transgene expression and thyroid-specific expression was verified by RNase protection analysis. Line 5215 was one of three lines established. (J:67120)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x C3H)F1
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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