The transgene contains the cardiac-specific mouse promoter, IRES, translation initiation sequence, loxP site, lacZ reporter gene with a STOP codon and polyadenylation sequence, loxP site, enteroviral protease 2a cleavage site, enteroviral protease 2a coding sequence and polyadenylation sequence. The pound symbol (#) is used when no line is specified and/or lines are pooled. Cre-mediated recombination is required to achieve expression of the protease. (J:128060)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count