The targeting construct introduced into the locus a CAG promoter, loxP site, neomycin resistance cassette, loxP2272 site, the intracellular domain encoding human cDNA, IRES, Venus gene, a polyadenylation sequence, loxP site and loxP2272 site. Cre-mediated recombination removed the selection cassette. (J:209193)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count