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An EGFP gene with a stop codon was fused to exon 11. Exon 12 was replaced with a floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. Western blot analysis confirmed the expression of a smaller than normal protein (~100 kDa). However, cell membrane localization of the truncated protein is normal. (J:209027)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
