The pancreas-specific rat insulin II promoter drives the expression of the lymphocytic choriomeningitis viral glycoprotein. Exons 2 and 3 of the beta-globin gene were ligated to the 3' end of the construct to provide splicing and polyadenylation signals. Immunohistochemistry confirmed protein expression in the pancreas. Two lines were established, Bln and Brx. However, the pound symbol (#) is used because the lines are pooled. (J:81285)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
--
--
11

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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