Log In|Sign Up
EN
I.M.A.G.E. clone BAC RP24-186D18 was modified to express a cDNA encoding humanized COP4 (also called channelrhodopsin-2 or ChR2) carrying an H134R (histidine 134 arginine) mutation fused to EYFP (ChR2(H134R)EFYP) under the control of the mouse Pcp2 gene regulatory elements. High expression is found in Purkinje cells of the cerebellum as well as rod bipolar cells of the retina. (J:201128)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
