The targeting vector inserted into the locus a CAG prmoter, floxed 2.7 kb neomycin resistance/stop cassette, codon optimized C. elegans glutamate-gated chloride channel (alpha and beta genes separated by a TaV 2A sequence), a second TaV 2A sequence, EYFP gene and woodchuck hepatitis virus posttranscriptional regulatory element (WPRE). Cre-mediated recombination is required to achieve expression of the reporter. (J:206513)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count