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The targeting construct introduced into the locus a floxed neomycin resistance/stop cassette and a fusion of the EBV B95-8 strain Lmp1 coding sequence encoding amino acids 1-190 and the human cDNA encoding amino acids 223-280. This fusion generates a constitutively active receptor that is only expressed after cre-mediated removal of the stop cassette. (J:137122)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
