The single-copy transgene comprises a chicken beta actin promoter followed by a loxP-flanked neomycin resistance cassette (neor) with a triple polyadenylation signal, a full-length cDNA encoding mouse T-box 1 protein (TBX1) with a Myc epitope tag, an internal ribosomal entry site (IRES) and a green fluorescent protein coding sequence. Upon cre recombinase-mediated recombination, neor is excised and the Tbx1 cDNA is expressed under control of the beta-actin promoter. (J:146886)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
--
Insertion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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