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The transgene construct was generated by fusing the codon-improved cre recombinase (icre) sequence with a nuclear localization signal, to the translation initiation codon of the Hmx3 (Nkx5-1) gene located in a bacterial artificial chromosome (BAC). An SV40 polyadenylation signal followed the cre sequence. This modified BAC was used to generated transgenic mice. (J:151793)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
