The MT-C retrotransposon element in intron 6 was deleted via TALEN mediated recombination. This abolishes expression of an oocyte specific isoform (Dicer1O) without altering expression of the somatic isoform (Dicer1S). The deletion is located at chr12:104,727,100-104,727,783 (m38/mm10). (J:203415)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
Intragenic deletion
--
1
13
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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