One loxP site was inserted just downstream of the 5' UTR and a second loxP site was located downstream of the FRT flanked PGK-neo cassette. The selection cassette was inserted just downstream of exon 3. Thus, exons 1-3 are flanked by loxP sites. (J:209127)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count