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A loxP site was inserted upstream of the microRNA region and an FRT flanked neo cassette and loxP site were inserted downstream of the region. Recombinase mediated recombination removed the neo cassette and the microRNA coding region. Expression of Mir128 was reduced by 80% in the brain of homozygous mice. (J:205260)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
