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EN
ENU induced a point mutation (T to A) that results in the missense amino acid substitution of arginine for tryptophan at position 932 (W932R). This mutation results in a failure of the product to localize to the cis-Golgi. Expression of the mutant protein in a cell line results in reduced enzymatic activity. (J:205339)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
