An FRT-flanked PGK-neo cassette is inserted into intron 1, followed by loxP-flanked exon 2. Flp-mediated recombinase removed the neo cassette, resulting in a loxP-flanked exon 2 allele. (J:202741)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count