Bmpr2^b2b2556Clo

This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a T to C substitution at nucleotide +2 after coding nucleotide 852 (c.852+2T>C, NM_007561) in intron 6, changing splice donor site T-GT to T-GC (which is assumed to be less efficient). (J:175213) Additional incidental mutations were detected in sequencing for the causative mutation, Bmpr2b2b2556Clo, and may be present in stocks carrying this mutation.