The construct consists of the TRE3G (a third-generation tet-responsive promoter), and EmGFP region, a fusion of Mirlet7a to a modified mir155 terminal loop, an SV40 polyadenylation signal, a 13 kb mouse Vil1 promoter, and a rtTA-M2 sequence. The Mirlet7a/mir155 fusion shRNA is not recognized by LIN28A or LIN28B. (J:202923)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F1
--
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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