A BAC clone (RP23-99k15) was modified using homologous recombination in bacteria to insert an NLS-cre-polyA cassette (nuclear localization signal-cre recombinase-polyadenylation sequence) at the ATG start codon of the Gpr88 gene. The Gpr88-cre fragment was excised, purified and injected into pronuclei of C%7BL/6 zygotes. One transgenic line was obtained. (J:207751)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
--
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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