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Improved cre (icre) cDNA was cloned downstream of the Defa6 promoter in a plasmid construct. A human growth hormone sequence was also present in the construct (Defa6-icre-hGH) which was linearized and used for pronuclear injection. 22 founders were produced and 2 lines were used for further characterization. A representative line was entered. (J:206084)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
