A loxP was inserted into the promoter region of Atg16l1, and a second loxP site and Frt-flanked neo cassette was placed in intron 1. Targeted mice were crossed to constitutive Flp expressing mice to remove the neo, leaving exon 1 floxed. (J:206084)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count