A loxP was inserted into the promoter region of Atg16l1, and a second loxP site and Frt-flanked neo cassette was placed in intron 1. Targeted mice were crossed to constitutive Flp expressing mice to remove the neo, leaving exon 1 floxed. (J:206084)
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A loxP was inserted into the promoter region of Atg16l1, and a second loxP site and Frt-flanked neo cassette was placed in intron 1. Targeted mice were crossed to constitutive Flp expressing mice to remove the neo, leaving exon 1 floxed. (J:206084)