The targeting construct introduced into the locus a floxed neomycin resistance/STOP cassette, a FLAG-tagged modified Phc cDNA with the L307R mutation (FM2), and IRES-EGFP. Cre-mediated recombination removed the selection/STOP cassette to allow for expression of the cDNA and reporter gene. (J:204987)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count