A targeting vector was designed to insert an FRT-flanked neomycin marker and a loxP site upstream of exon 2 of the Gfi1b gene and to insert a second loxP site between exons 5 and 6. Correctly targeted ES cells were treated with Flp to excise the neo resistance marker. (J:207446)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count