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EN
Exon 16 was replaced with a modified one in which a point mutation (T-to-C) results in the amino acid substitution of leucine with proline at position 799 (p.L799P). This mutation is orthologous to the human mutation p.Leu811Pro observed in patients with loss of pain perception. Cre-mediated recombination removed a floxed neomycin resistance cassette. (J:206848)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
