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The human APP695 containing the Swedish K670N and M671L and Artic E693G mutations is under the control of the prion protein promoter. The pound symbol (#) is used because the line is not specified, although the line used has a 6-fold overexpression of APP compared to endogenous APP levels. (J:128080)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
