The transgenic construct contains a genetically encoded calcium indicator, GCaMP6, under the control of the tetO, tetracycline-responsive regulatory element. GCaMP consists of a circularly permutated green fluorescent protein (cpGFP), the calcium-binding protein calmodulin (CaM), and CaM-interacting M13 peptide. Line (G6s)2 was generated. (J:229378)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count