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TALEN targeting of exon 15 for homologous recombination with a synthetic oligodeoxynucleotide induced a point mutation (C to T) that results in the amino acid substitution of leucine for phenylalanine at position 517 (P517L). Founder F36 exhibit the intended point mutation and an additional nucleotide substitution G to A in the TALEN-Fus15B targeting sequence. (J:201579)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
