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A BAC (RP23-340E18) containing the Gck locus was modified by inserting cre recombinase with a nuclear localization sequence and a polyA at the ATG site in exon 1 of Gck by homologous recombination in bacterial cells. The purified construct was injected into C57BL/6 pronuclei to generate founders. Line numbers are not available. (J:206002)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
