The gene trap vector inserted in intron 3 and is predicted to result in a protein fusion to the 3rd extracellular leucine rich repeat of the ectodomain. Western blot and immunoblot analysis indicated that protein levels are severely reduced in embryonic lysates from homozygous mice. (J:202451)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv
Gene trapped
Insertion of gene trap vector
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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