The Tg 11.5kb-GFP transgene was designed with an enhanced green fluorescent protein (EGFP) driven by 11.5kb of the inositol polyphosphate-5-phosphatase D (Inpp5d) promoter, followed by a polyadenylation site. Lines A,B C and D were established, however, Line B lacks expression of the transgene. Results are primarily from Line D, although all three lines have similar in vivo expression patterns. Line D has 11 copies. (J:163731)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x CBA/J)F1
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Insertion
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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