An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 14. An additional loxP site was inserted downstream of 21. Flp-mediated recombination removed the resistance cassette and left exons 14 through 21 floxed. (J:206350)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count