A minigene construct was generated with a 2.5 kb fragment of the 5' promoter region of the Jdp2 gene, cre recombinase with a nuclear localization signal (NLS), an IRES site, and an NLS-lacZ sequence followed by an SV40 polyA signal. The linearized construct was used for microinjection of fertilized FVB/N oocytes. 25 founder lines were produced, and were crossed to lacZ (R26R-lacZ) or GFP (Z/EG) reporter animals to assess cre functionality. Numbers for maintained lines are not available at this time. (J:206564)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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