A floxed neomycin resistance cassette was inserted upstream of exon 7, which contains the membrane spanning domains M1-M3. An additional loxP site was inserted dowsntream of exon 7. Cre-mediated recombination removed the selection cassette and left exon 7 floxed. (J:202763)
Basic Information
129S4/SvJae-Tg(Prm-cre)70Og
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count